Brodmann's Interactive Atlas

(Superior Temporal Gyrus - Part of Wernicke's area)

Associated Functions
Reviewer's note

Damage of BA22 in the left hemisphere results in Wernicke's aphasia (language disorder characterized by fluent speech, paraphasias -wrongly produced words-, and language understanding defects). Wernicke's aphasia however, is quite variable, depending on the exact location and extent of the brain damage. The diversity of linguistic functions observed in functional studies reinforces its crucial role in language reception and processing. Sounds with complex spectral intensity and temporal structures (words, speech, music) activates spatially extensive associative auditory areas in both hemispheres (BA 21/22), but right BA22 plays the fundamental role in nonverbal sound processing. As it is an auditory association area, its activation during non-auditory related tasks seems intriguing, e.g., “remembered saccades”; however, it should be noted that “remembered saccades” activates an extensive network including the striate and extra-striate cortex, posterior parietal cortex, frontal eye fields, supplementary motor area, insula, cingulate, thalamus, midbrain, cerebellum and BA22; BA22 participation is thus quite tangential. “Deductive reasoning” activates a complex brain network including in the left BA21/22/32/37/45/46/47 (kind of “executive function circuitry”), emphasizing that reasoning is partially mediated by language .
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